President Biden and other world leaders, including António Guterres, the secretary general of the United Nations, are gathering virtually for a small panel discussion on Wednesday to kick off a global summit, convened by the White House, aimed at forging a global consensus around a plan to fight the coronavirus crisis.
The opening discussion, “Call the World to Account and Vaccinate the World,” will be moderated by Linda Thomas-Greenfield, Mr. Biden’s ambassador to the United Nations. Participants will include other presidents and prime ministers, including President Matamela Cyril Ramaphosa of South Africa and Prime Minister Boris Johnson of the United Kingdom.
White House officials have said that Mr. Biden’s message to the group will be that the United States cannot fight the pandemic, or address the global vaccine shortage, on its own. Earlier Wednesday, Pfizer-BioNTech announced that it had struck a deal with the Biden administration to sell the United States an additional 500 million doses of its coronavirus vaccine, to be donated to nations that need them.
Drug company executives, philanthropists and leaders of nonprofit organizations have also been invited to the summit, which is being convened by Mr. Biden to coincide with the United Nations General Assembly meeting in New York. Administration officials say it is the largest gathering of heads of state to date to address the global pandemic.
Mr. Biden has been under intense pressure from global health experts to do more to address the vaccine shortage. Less than 10 percent of the population of poor nations — and less than 4 percent of the African population — has been fully vaccinated against Covid-19. Covax, the W.H.O.-backed international vaccine initiative, is behind schedule in delivering shots to the low- and middle-income nations that need them the most.
At a briefing held by Physicians for Human Rights earlier this week, Dr. Soumya Swaminathan, the chief scientist of the World Health Organization, sounded a note of urgency and issued a plea for nations to work together to distribute vaccines in a coordinated — and equitable — fashion. She also urged countries to share their excess supplies.
“A country by country approach, a nationalistic approach, is not going to get us out of this pandemic,” she said. “And that’s where we are today.”
Scientific advisers to the Centers for Disease Control and Prevention are meeting on Wednesday and Thursday to decide which Americans should get booster shots of the Pfizer-BioNTech coronavirus vaccine — and when.
The committee’s discussions are normally a scientific affair of little interest to most people. But this meeting is likely to be closely watched — the stakes are high. It follows a dramatic exchange at the Food and Drug Administration on Friday, when advisers overwhelmingly rejected a proposal to offer Pfizer booster shots for Americans over 16, but then voted unanimously in favor of third doses for some high-risk people and those older than 65.
The role of the C.D.C. advisers at the two-day meeting is to decide who belongs in those high-risk groups. Depending on their verdict, booster shots could be offered to most Americans — or only to a select few.
If the F.D.A. authorizes the Pfizer-BioNTech booster dose, advisers to the C.D.C will vote on Thursday to make their recommendations. But it is likely to be too late for the Biden administration, which had planned to begin offering third doses this week to most fully vaccinated adults in the United States.
At the meeting on Friday, senior scientists at Pfizer and the Israeli Ministry of Health presented data they said indicated waning immunity in people who received the Pfizer vaccine months earlier. Boosting immune defenses with a third shot has made a difference in Israel, they said, and could stem the tide of infections in the United States.
The F.D.A. advisers also evaluated data from the C.D.C. on the trajectory of the virus in the United States, as well as summaries from several studies on the effectiveness of the vaccines.
But after reviewing the evidence, the scientists on the committee concluded that while protection against infection may be waning, especially in older adults, the original two-shot regimen still offers excellent protection against severe illness and hospitalization in most people.
“It’s unclear that everyone needs to be boosted, other than a subset of the population that clearly would be at high risk for serious disease,” said Dr. Michael G. Kurilla, a committee member and official at the National Institutes of Health.
One key difference between Israel and the United States may explain why the two countries have had different experiences with the vaccine: The countries define severe illness differently.
In Israel, anyone with an accelerated respiratory rate and an oxygen level of below 94 percent is severely ill. By contrast, the C.D.C. reserves that category for people who are sick enough to be hospitalized, said Dr. Sara Oliver, a C.D.C. scientist who presented the American data.
Some committee experts said they also did not feel comfortable offering booster shots to young people who may not need them, when the risks of a third dose are unknown.
The vaccines have been tied to rare cases of myocarditis, inflammation of the heart, in younger people. The risk is very small, and studies have shown that Covid-19 is much more likely to cause the condition.
Last week brought other research in support of the F.D.A. committee’s decision, including one paper by an international team of scientists that analyzed dozens of studies and concluded that the world would be better served by using vaccine doses to protect the billions who remain unvaccinated.
The authors of that study included the top two vaccine experts at the F.D.A., who announced plans to leave the agency this fall. Their departure is in part in protest of the Biden administration’s push for boosters before federal scientists and regulators had reviewed the evidence.
Brazil’s health minister announced that he had tested positive for the coronavirus on Tuesday in New York, where he was attending the United Nations General Assembly along with the country’s defiantly unvaccinated president, Jair Bolsonaro.
The health minister, Marcelo Queiroga, tweeted that he would quarantine in the United States and was “following all health safety protocols.” Dr. Queiroga, who is a cardiologist, received the CoronaVac vaccine, made by Beijing-based Sinovac, early this year.
Dr. Queiroga had accompanied Mr. Bolsonaro during his visit to New York for the U.N. meeting, and was seen on video shaking hands with Britain’s prime minister, Boris Johnson, when Mr. Johnson met Mr. Bolsonaro on Monday.
Before being diagnosed, Dr. Queiroga participated in meetings in New York with United Nations Secretary General Antonio Guterres and with President Andrzej Duda of Poland.
On Monday night, Dr. Queiroga made headlines in Brazil after he was filmed giving anti-Bolsonaro demonstrators the middle finger as he and other members of the government delegation left a dinner at the residence of the country’s ambassador to the United Nations.
The president’s office said in a statement issued late Tuesday that Dr. Queiroga would remain in the United States while he recovers and said he was “doing well.”
“We also inform that the other members of the delegation tested negative for the virus,” the statement said.
Dr. Queiroga had a busy agenda in New York. He had breakfast with a group of investors; participated in a meeting with Brazil’s first lady, Michelle Bolsonaro; paid tribute at the Sept. 11 memorial; and spoke to senior officials at the World Health Organization.
Dr. Queiroga became Mr. Bolsonaro’s fourth health minister in March. His tenure has been marred by allegations that senior ministry officials sought kickbacks as they negotiated the purchase of Covid-19 vaccines.
Mr. Bolsonaro’s handling of the pandemic in South America’s largest country has been widely criticized. He has repeatedly downplayed the threat the virus posed, and his government was slow to secure access to vaccines even as Covid-19 overwhelmed hospitals and killed more than 590,000 people in Brazil.
On Tuesday, Mr. Bolsonaro used his speech at the General Assembly to defend the use of ineffective drugs to treat the coronavirus and argued that doctors should have had more leeway in administering untested medications for Covid-19. The far-right president added that he had been among those who recovered after “off-label” treatment with a malaria drug that studies have found ineffective to treat the disease.
Mr. Bolsonaro, who had a mild case of Covid-19 in July of last year, has said he was in no hurry to get vaccinated, which made for an awkward exchange during his meeting with Mr. Johnson, who hailed the AstraZeneca vaccine, which was developed in Britain at Oxford University.
“Get AstraZeneca vaccines,” Mr. Johnson said. “I’ve had it twice.”
Mr. Bolsonaro pointed to himself and said: “Not yet.”
His unvaccinated status also created hurdles in New York, where restaurants require that patrons show proof of inoculation for indoor seating. On Sunday, one of Mr. Bolsonaro’s ministers posted a photo on Twitter of the president eating pizza while standing on the street alongside several top aides — including Dr. Queiroga.
As President Biden convenes heads of state for a Covid-19 summit on Wednesday, pressure is growing on American drug companies — particularly Moderna, the upstart biotech firm that developed its coronavirus vaccine with billions of dollars in taxpayer money — to share their formulas with manufacturers in nations that desperately need more shots.
Last year’s successful race to develop vaccines in extraordinarily short order put companies like Moderna and Pfizer in a favorable light. But now, with less than 10 percent of the population in many poor nations fully vaccinated and a dearth of doses contributing to millions of deaths, health officials in the United States and abroad are pressing the companies to do more.
The Biden administration has privately urged both Pfizer and Moderna to enter joint ventures with contract manufacturers with the aim of providing vaccines to low- and middle-income countries, according to a senior administration official.
Those talks led to an agreement with Pfizer, announced Wednesday morning, to sell the United States an additional 500 million doses of its vaccine at a not-for-profit price — rather than license its technology — to donate overseas.
The discussions with Moderna have not been fruitful, said the official, who expressed deep frustration with the company but requested anonymity to discuss sensitive information.
A coalition of major drug and vaccine manufacturers in developing countries around the world is drafting an appeal to Mr. Biden asking him to press the companies more aggressively.
The World Health Organization has also had trouble getting Moderna to the negotiating table, according to Dr. Martin Friede, a W.H.O. official, and Charles Gore, who runs a United Nations-backed nonprofit organization, Medicines Patent Pool. Both are working with a W.H.O.-backed technology transfer hub in South Africa.
“We would love to get a discussion with Moderna, about a license to their intellectual property — this would make life so much simpler, but for the moment all attempts have resulted in no reply,” Dr. Friede said.
President Biden is convening a panel of 30 scientific advisers — in fields as diverse as agriculture, biochemistry and computer engineering, ecology, nanotechnology and neuroscience — to advise the White House on addressing future pandemics, addressing climate change and a range of other global challenges.
Mr. Biden will announce the new President’s Council of Advisors on Science and Technology — to be known by the acronym PCAST — in a video the White House plans to release Wednesday morning. The White House describes the group as a “direct descendant” of the scientific advisory committee established by President Dwight Eisenhower in 1957 after the Soviet Union launched the first Sputnik satellite, beating the United States in the race to space.
The new council includes two Nobel laureates and five MacArthur “genius” grant recipients, as well as two former Cabinet secretaries and a former astronaut who was the first woman to dive into the deepest part of the Earth’s oceans. Half of its members, including two of its three co-chairs, are women. (The other co-chair is Eric Lander, who heads the White House Office of Science and Technology Policy).
“This PCAST will see new possibilities to create good jobs, and power American workers, and grow the economy for everyone, to change the course of human health and disease, to tackle the climate crisis with American innovation and to lead the world in technologies,” the president says in the video.
The panel has been nine months in the making. Mr. Biden asked Frances Arnold, a Nobel Prize-winning biochemical engineer, and Maria T. Zuber, a geophysicist and planetary scientist who was the first woman to lead a NASA planetary mission, to be co-chairs before he was inaugurated.
Dr. Arnold and Dr. Zuber spent months combing through résumés to submit to the president, and said in a joint interview that scientists were eager to serve, particularly in the wake of the administration of former President Donald J. Trump, who many scientists feel devalued their profession. No one they asked said no, and all are serving as volunteers.
“The almost utter dismissal of science as the basis for decision-making by the previous administration was tremendously dispiriting, and played a large role in the alacrity with which I made that decision to take on this new job,” said Dr. Arnold, a professor of chemical engineering, bioengineering and biochemistry at the California Institute of Technology.
The group has not yet held its first meeting or set an agenda. But Dr. Lander, who served on former President Barack Obama’s PCAST, said he would be surprised if the group “did not have a lot of interest in using the learning from this pandemic to think really fundamentally about public health system and how it could be improved.”
An earlier version of this item misstated the timing of President Biden’s video announcing the new advisory council. The White House planned to release it Wednesday morning, not Thursday morning.
The Organization for Economic Cooperation and Development said on Tuesday that a global economic recovery from the pandemic was finally taking hold, but it inched back its forecast for worldwide economic growth and warned that the rebound was benefiting wealthier countries more than the developing world as vaccine distribution occurs at an uneven pace.
Countries that have made big strides toward vaccinating most of their populations are bouncing back much more quickly than those that are still struggling to obtain shots, the organization said, raising a host of related economic problems that are affecting global supply chains and pose a risk for the future.
“The global shock that pushed the world to the worst recession in a century is now fading, and we’re now projecting the recovery will bring growth back to its pre-crisis trend,” Laurence Boone, the organization’s chief economist, said in a news briefing.
But vaccination rates remain varied, and many low-income countries and emerging markets, with the exception of China, are still far behind, Ms. Boone added. “A failure to vaccinate globally puts all of us at risk,” she said.
The warnings came as the O.E.C.D. released its semiannual economic forecast, in which it lowered its outlook for global growth, the U.S. economy and emerging markets, but raised its outlook for Europe.
The global growth outlook for 2021 was revised down slightly to 5.7 percent, from 5.8 percent.
Schools have largely reopened this fall, but life is far from normal for parents of young children. One reason is that child care — for children too young for school, and for the hours before and after school — is operating at 88 percent of its prepandemic capacity. Even before the pandemic, child care did not cover everyone who needed it.
The shortage is partly because of the pandemic. Some centers went out of business after lockdowns early on. Because children under 12 are not yet eligible for vaccines, many programs are enrolling fewer children to limit potential exposure.
But the biggest reason for the shortages, child care providers across the country said, is that they can’t find people to hire.
Eight in 10 providers said they were experiencing a staffing problem, and half said hiring was harder than before the pandemic, according to a survey over the summer of 7,500 of them by the National Association for the Education of Young Children.
Half said they were serving fewer children as a result of hiring problems, and a quarter had reduced their hours. The lack of child care is also contributing to other labor shortages, because many parents who can’t find reliable child care can’t return to work.
Child care providers face challenges like those in many other service industries that are unable to find enough workers: low pay and little job stability. The median hourly pay is $12, and 98 percent of occupations pay more, according to data from the Center for the Study of Child Care Employment at the University of California, Berkeley.
Turnover is high in early childhood education, and jobs caring for school-aged children are only a few hours a day and often end in the summer.
Child care has additional challenges. Some people are hesitant to work with unvaccinated children. The job requires more qualifications, including background checks, certifications and even college degrees in some areas, than the stores and restaurants that are paying more.
Yet child care centers have not responded the way some other industries have — by significantly raising wages and expanding benefits.
Australia, which had planned to retain heavy international travel restrictions until mid-2022, now plans to open up months ahead of schedule.
In a speech on Tuesday, Dan Tehan, the minister for trade, tourism and investment, encouraged Australians to keep getting vaccinated and “to stick to the national plan that will see our international border open up, at this rate, by Christmas, at the latest.”
Mr. Tehan’s remarks at the National Press Club of Australia were a departure from the country’s earlier plans to keep its severe lockdown and travel restrictions in place.
Australia’s borders “are closed,” according to the Department of Health’s website. “There is a ban on all overseas travel,” it says, unless an exemption from the government is granted.
The only people allowed inside the country, according to the site, are Australian citizens, permanent residents and their immediate family members. Quarantine-free travel to and from New Zealand was temporarily suspended on Tuesday.
In his speech on Tuesday, Mr. Tehan also said that “hopefully, at the latest by Christmas,” Australians would be able to travel “with a QR code linked to their passport which will be able to show a proof of vaccination.”
In other news from around the globe:
New Zealand, which has pursued a zero-Covid strategy, may not get back to eliminating all coronavirus cases in the community, a senior health official there said, according to Reuters. “The important thing is we are going to keep finding any infections and basically continue to contact trace, test and isolate people so that we stop the virus circulating in the community,” Ashley Bloomfield, the director general of health, told Radio New Zealand.